Is your Transformer Prime freezing up after the Ice Cream Sandwich update was issued a few weeks ago? There is a fix, that seems to work on most units experiencing random freeze ups. Apparently according to the guys over at XDA Forums the below fix works on most of the units that have bee returned due to the freeze up issue.
One option to try is to revert back to the last Honeycomb image through the manual update process, set the unit power mode to balanced performance and screen brightness manually to 50%, and then manually update to the latest ICS build using these instructions – http://service.asus.com/TF201_fwupdate. You will need a fully charged battery and have the system plugged into AC power. This worked on a couple of returned units but not on all units.
Same goes for the BT/WiFi fallout issue (forum thread), which would lead to the Bluetooth signal degrading when streaming media via WiFi, except that there’s no manual workaround available in case you don’t want to wait for the official fix sometime next month.